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The Valle de Bío-Bío wine-growing area (also VIII Bío-Bío Región, Bío-Bío Valley) lies 500 kilometres south of the capital Santiago in Chile. Together with the Itata and Malleco areas, it forms the Valle Sur region. Bío-Bío is followed only by the small Malleco as the southernmost Chilean area. The climate is cool and windy with sufficient rainfall. The vineyards are located along the Bío-Bío river on high-yield, sandy and stony soils from river deposits. In contrast to the more northern Chilean areas, no artificial irrigation is necessary due to sufficient rainfall

It is mainly the traditional Moscatel de Alejandría(Muscat d'Alexandrie) and País(Listán Prieto) that are grown here. Other varieties are Sauvignon Blanc, Chardonnay, Riesling, Gewürztraminer and Pinot Noir. Mainly simple mass wines are produced, but increasingly also quality wines from international varieties. The Viña Canata winery describes itself as the southernmost winery in the world (but others also claim this). Other producers are Carpe Diem, Don Francisco and VinSur.

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