The Greek physician Hippocrates (460-377 BC) was born on the island of Kos in the eastern Aegean Sea and is known as the father of medicine. The "Hippocratic Oath" used to define the moral and ethical duties of the doctor. However, this oath is no longer officially required today. Wine plays an important role in almost all the medicines he handed down. In his work "Corpus Hippocraticum", the health aspects of drinking wine are pointed out in the form of therapeutic recommendations using numerous examples. Among other things, he prescribed wine to cool fever, as a general germicidal agent, as a diuretic and as a tonic for convalescents. Hippocrates gave detailed information and recommended certain wines according to the ailment or advised against drinking wine at all. The "Manica Hippocratis" (sleeve of the hippo act), a muslin filter bag in use until the Middle Ages, and the spiced wine Hypocras, which is similar to mulled wine, are named after the doctor. In the second century A.D., there was a veritable Hippocrates renaissance, to which the Greek physician Galenos of Pergamon (129-216) contributed.