The Italian physician and naturalist Andrea Bacci (1524-1600) from Sant'Elpidio a Mare in today's Marche region studied medicine in Siena and Rome, where he was promoted by Modestino Cassini, the personal physician of Emperor Maximilian II (1527-1576). Later Bacci became the personal physician of Pope Sixtus V (1521-1590). He particularly recommended the wines from Liguria, e.g. the Rossese variety, to which he attributed almost magical powers and said " that they could even make stones blossom". He taught botany and pharmacology in Rome and wrote numerous pharmacological and toxicological writings. In his main work on natural history, "De Naturalis Vinorum Historia", he described Italian wines from many regions. He reports that the Carthaginian commander Hannibal (247-183 B.C.) cured the tired horses of his army by drinking a large quantity of Conero (today DOC Rosso Conero) when marching against Rome. He also praises the excellent wines of Abruzzo and calls Sardinia the "island of wines".
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