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Abbreviation for "Peptide Nucleic Acid - Fluorescence In Situ Hybridisation". A peptide is an organic chemical compound resulting from the linkage of several amino acids arranged in a defined order (sequence). It is a medical-diagnostic analytical method with which certain DNA and RNA sequences can be localised in tissues, cells, cell nuclei and chromosomes in minute quantities. An artificially produced probe made of a nucleic acid is used, which "hybridises" the nucleic acid to be detected, i.e. binds it and makes it visible. The term "in situ" refers to the fact that the detection is carried out directly in the respective structure and not, for example, biochemically in a test tube. The PNA probes used are marked with a fluorescent dye. The PNA-FISH method is mainly used in medicine to detect and identify pathogens in human blood.

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Egon Mark

For me, Lexicon from wein.plus is the most comprehensive and best source of information about wine currently available.

Egon Mark
Diplom-Sommelier, Weinakademiker und Weinberater, Volders (Österreich)

The world's largest Lexicon of wine terms.

26,261 Keywords · 46,882 Synonyms · 5,322 Translations · 31,594 Pronunciations · 193,211 Cross-references
made with by our author Norbert F. J. Tischelmayer. About the Lexicon