The winery is located in the city of Würzburg in the German wine region of Franconia. It was founded in 1576 by Prince Bishop Julius Echter von Mespelbrunn (1545-1617) following the example of the Hospices de Beaune. For this purpose he acquired the "Judengarten" (Jewish Garden) outside the old town. The Prince Bishop transferred sufficient income and extensive property to his foundation to cover the tasks already during his lifetime, which included vineyards, among others in the world-famous Würzburger Stein location, as well as extensive agricultural and forestry properties. To this day, a home for the elderly, a hospice, two palliative wards, a school of nursing and other welfare facilities are maintained. The foundation's task of caring for the sick was taken over by the Klinikum Würzburg Mitte in early 2017. The 250-metre-long cellar corridor, built in 1699 by Antonio Petrini, is the longest wooden barrel cellar in Germany and is lined with 220 oak barrels. There is the company's own vinotheque "Weineck Julius Echter" opposite the main entrance to the Juliusspital. As administrator is Dipl. Ing. agr. Horst Kolesch, as cellar master Dipl. Önologe Nicolas Frauer and Helmut Klüpfel.
The vineyards cover around 180 hectares and are distributed throughout Franconia in the following municipalities: Bürgstadt with Mainhölle; Dettelbach with Berg-Rondell; Escherndorf with Lump; Iphofen with Canon and Julius-Echter-Berg; Randersacker with Pfülben and Teufelskeller; Rödelsee with chef; Thüngersheim with Johannisberg; Volkach with Karthäuser; as well as Würzburg with Abtsleite, fortress view in Monopol, Innere Leiste, Pfaffenberg and Stein. The Vogelsburg Monastery was maintained by Augustinian Sisters and was handed over with the vineyards to the Juliusspital Foundation in 2011. The white wine varieties Silvaner, Riesling, Müller-Thurgau,Pinot Blanc and PinotGris, as well as red wine varieties with mainlyPinot Noir, Domina and others are cultivated. After fermentation, the wines are stored on the fine yeast for a long time. The maturing process is combined in stainless steel tanks and in large oak barrels, some of which are over a hundred years old. Organic wines are also produced from the three hectares of vineyards at the Vogelsburger Gap. The winery is a member of the VDP (Verband deutscher Prädikatsweingüter).